Product Description:
Polymer Factory's bis-MPA NHBOC-hydroxyl dendrons are monodisperse, multifunctional scaffolds with 1 protected amine focal point and an exact number of OH surface groups. After deprotection, the amine focal point can be used for EDC/DCC coupling or coupling to NHS esters to produce highly functional materials.  Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.
 
Related Publications
 
Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981                               
Fluoride-Promoted Esterification (FPE) Chemistry: A Robust Route to Bis-MPA Dendrons and Their Postfunctionalization - Molecules, 2016, 21(3), 366                       
Fluoride‐Promoted Esterification with Imidazolide‐Activated Compounds: A Modular and Sustainable Approach to Dendrimers -  Macromolecules, 2005, 38 (9), 3663-3678                                                                                                                                                   
Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879                                     
Synthesis and in Vitro Evaluation of Monodisperse Amino-Functional Polyester Dendrimers with Rapid Degradability and Antibacterial Properties - Angew. Chem. Int. Ed., 2015, 54, 2416-2419                                                                                                                               
Evaluation of Amino-Functional Polyester Dendrimers Based on Bis-MPA as Nonviral Vectors for siRNA Delivery - Molecules, 2018, 23 (8), 2028