Product Description:
Polymer Factory's bis-MPA Acetylene-NHBOC dendrons are monodisperse, multifunctional scaffolds with 1 alkyne focal point and an exact number of protected amine surface groups. After deprotection, the amine surface groups can be used for EDC/DCC coupling or coupling to NHS esters, while the acetylene focal point can be used for click chemistry conjugation such as CuAAC and thiol-yne coupling, to yield highly functional materials. Our bis-MPA polyester scaffolds are biodegrable and have low cytotoxicity, making them ideal candidates for use in biological research applications.
Related Publications
- Stability and biocompatibility of a library of polyester dendrimers in comparison to polyamidoamine dendrimers - Biomaterials, 2012, 33 (7), 1970-1981
- Multivalent, bifunctional dendrimers prepared by click chemistry - Chem. Comm., 2005, 0, 5775-5777
- Structurally Diverse Dendritic Libraries: A Highly Efficient Functionalization Approach Using Click Chemistry - Macromolecules, 2005, 38 (9), 3663-3678
- Dendritic architectures based on bis-MPA: functional polymeric scaffolds for application-driven research - Chem. Soc. Rev., 2013, 42, 5858-5879
- Synthesis and in Vitro Evaluation of Monodisperse Amino-Functional Polyester Dendrimers with Rapid Degradability and Antibacterial Properties - Biomacromolecules, 2017, 18 (12), 4323-4330
- Evaluation of Amino-Functional Polyester Dendrimers Based on Bis-MPA as Nonviral Vectors for siRNA Delivery - Molecules, 2018, 23 (8), 2028
bis-MPA NHBoc Dendron, Acetylene Core, Generation 4
SKU: PFDO-040413
PriceFrom €779.00
- Product Type: Dendron
- Focal Point: Acetylene
- Product Code : PFd-G4-Acetylene-NHBOC
- End Group Functionality: NHBOC
- Generation: 4
- Number of Surface Groups: 16
- Theoretical MW: 4536,94 g/mol
- Form: White Powder
- Purity: >95%
- Delivery Time: 5 - 8 Working Days
- SOPs - Deprotection, EDC, NHS & CuAAC